Artvigil 150 (armodafinil) and Modalert (modafinil) are both wakefulness-promoting medications used to treat conditions like narcolepsy, obstructive sleep apnea, and shift work sleep disorder. The primary difference lies in their composition: Artvigil contains armodafinil, the R-enantiomer of modafinil, offering a longer half-life and more sustained effects, potentially making it more effective for prolonged wakefulness. Modalert (modafinil), on the other hand, has a slightly faster onset but may not last as long for some users. Artvigil is often perceived as "milder" and more focused, while Modalert is sometimes considered "stronger" with a more stimulating effect. Both medications have similar side effects, and the choice between them depends on individual response and therapeutic needs.